Design and engineering of water-soluble light-harvesting protein maquettes

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Design and engineering of water-soluble light-harvesting protein maquettes

The Johnson Research Foundation and Dep University of Pennsylvania, Philadelphia, med.upenn.edu The ARC Centre of Excellence for Electroma Research Institute, University of Wollongong N Carolina State University, Department of University of Otago, Department of Chemis † Electronic supplementary information and supplementary Fig. S1–10. See DOI: 1 ‡ These authors contributed equally to th Cite t...

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Design and engineering of water-soluble light-harvesting protein maquettes† †Electronic supplementary information (ESI) available: Experimental methods and supplementary Fig. S1–10. See DOI: 10.1039/c6sc02417c Click here for additional data file.

Natural selection in photosynthesis has engineered tetrapyrrole based, nanometer scale, light harvesting and energy capture in light-induced charge separation. By designing and creating nanometer scale artificial light harvesting and charge separating proteins, we have the opportunity to reengineer and overcome the limitations of natural selection to extend energy capture to new wavelengths and...

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Design principles of photosynthetic light-harvesting.

Photosynthetic organisms are capable of harvesting solar energy with near unity quantum efficiency. Even more impressively, this efficiency can be regulated in response to the demands of photosynthetic reactions and the fluctuating light-levels of natural environments. We discuss the distinctive design principles through which photosynthetic light-harvesting functions. These emergent properties...

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Rational design of 'water-soluble' bacteriorhodopsin variants.

We have explored the interchangeability of soluble and membrane proteins by attempting to render a helical membrane protein 'water soluble' through mutation of its lipid-exposed residues. Using an atomic resolution structure of bacteriorhodopsin (bR), two different strategies were developed to identify lipid-exposed residues for mutation. In the first strategy all residues in trimeric bR with s...

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ژورنال

عنوان ژورنال: Chemical Science

سال: 2017

ISSN: 2041-6520,2041-6539

DOI: 10.1039/c6sc02417c